Proposal overview: This project aims to address the controversies in patient and treatment selection for ventricular functional mitral valve disease by conducting new, multi-center studies to gain insights into the current state of treatment and provide evidence-based recommendations for patient management. The project will provide an overview of the current surgical and transcatheter treatments, compare the clinical and echocardiographic results of these treatments at 1-year post-intervention in real-world settings, assess the potential for left ventricular reverse remodeling with various treatment options, and compare the impact of different surgical repair techniques on diastolic mitral valve performance at 1-year post-surgery.

Inclusion period: 01-10-2024 until 30-09-2025 (with follow-up until 2026).

Initiator: Anton Tomšič, MD, PhD (PI: Prof. Evaldas Girdauskas, MD, PhD) from Augsburg University hospital.

Status: Proposal is approved, centers are recruited.